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Allergic rhinitis: managing the pediatric spectrum.

Eli O Meltzer1

  • 1Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA. EOMELTZER@aol.com

Allergy and Asthma Proceedings
|April 8, 2006
PubMed
Summary

Allergic rhinitis (AR) is a common childhood condition impacting health and quality of life. Effective management involves pharmacologic treatments like antihistamines and intranasal corticosteroids, alongside allergen immunotherapy.

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Area of Science:

  • Pediatrics
  • Allergy and Immunology
  • Pharmacology

Background:

  • Allergic rhinitis (AR) is the most prevalent chronic pediatric disease, with rising incidence.
  • AR negatively affects children's health, quality of life, and can lead to asthma.
  • Allergen avoidance, while recommended, is often impractical for managing AR.

Purpose of the Study:

  • To review current pharmacologic treatment options for pediatric allergic rhinitis.
  • To discuss the risk/benefit profiles of various medications used in AR management.
  • To highlight considerations for effective AR treatment in children.

Main Methods:

  • Review of existing literature on pediatric allergic rhinitis pharmacotherapy.
  • Analysis of first-line and alternative pharmacologic agents.
  • Discussion of adjunctive therapies and practical considerations.

Main Results:

  • Second-generation antihistamines and intranasal corticosteroids are preferred first-line treatments.
  • Other options include decongestants, leukotriene-receptor antagonists, and cromolyn sodium.
  • Allergen immunotherapy serves as a valuable adjunctive treatment.

Conclusions:

  • Pharmacologic interventions are crucial for managing pediatric allergic rhinitis.
  • Medication selection requires careful consideration of risk/benefit, compliance, and convenience.
  • A multi-faceted approach including pharmacotherapy and potentially immunotherapy optimizes AR management in children.

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