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Managing impairment in patients with allergic rhinitis
Jeffrey Stokes1, Eric Fenstad, Thomas B Casale
1Division of Allergy/Immunology, Department of Medicine, Creighton University, Omaha, Nebraska 68131, USA.
Allergy and Asthma Proceedings
|April 8, 2006
Summary
Allergic rhinitis significantly impacts quality of life and performance due to its symptoms and treatments. Second-generation antihistamines are preferred over older, sedating options for managing allergic rhinitis with less impairment.
Area of Science:
- Allergy and Immunology
- Pharmacology
- Clinical Medicine
Background:
- Allergic rhinitis is a prevalent condition affecting adults and children.
- A significant complication is reduced quality of life and impaired daily functioning.
- Both the condition and its treatments can cause impairment.
Purpose of the Study:
- To review the impact of allergic rhinitis on patient quality of life and performance.
- To compare the impairing effects of first-generation versus second-generation antihistamines.
- To establish preferred antihistamine use in allergic rhinitis management.
Main Methods:
- Literature review of allergic rhinitis and antihistamine treatments.
- Analysis of impairment associated with different antihistamine generations.
- Evaluation of quality of life and performance data in allergic rhinitis patients.
Main Results:
- Allergic rhinitis negatively affects work and school performance.
- First-generation antihistamines cause significant impairment, even without sedation.
- Second-generation antihistamines are generally less impairing than first-generation agents.
Conclusions:
- Second-generation antihistamines are the preferred choice for treating allergic rhinitis when antihistamines are indicated.
- Minimizing treatment-related impairment is crucial for improving patient outcomes.
- Effective management of allergic rhinitis requires consideration of both symptom control and functional impact.
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