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Laryngopharyngeal reflux.

Ramon A Franco1

  • 1Massachusetts Eye and Ear Infirmary, Division of Laryngology, Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02114, USA. Ramon_Franco@meei.harvard.edu

Allergy and Asthma Proceedings
|April 8, 2006
PubMed
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Laryngopharyngeal reflux (LPR) involves stomach contents moving into the throat, causing voice, cough, and swallowing issues. Effective LPR management requires lifestyle changes and high-dose proton pump inhibitors.

Area of Science:

  • Gastroenterology
  • Otolaryngology

Background:

  • Laryngopharyngeal reflux (LPR) is the backward flow of gastric contents into the laryngopharynx.
  • LPR often presents with laryngeal symptoms like dysphonia, chronic cough, and globus sensation, frequently without typical heartburn.

Purpose of the Study:

  • To elucidate the diagnostic and therapeutic challenges of Laryngopharyngeal reflux.
  • To emphasize the importance of LPR recognition for allergists managing chronic cough and related symptoms.

Main Methods:

  • Review of LPR pathophysiology, clinical manifestations, and associated conditions.
  • Discussion of current treatment modalities including dietary changes, behavioral modifications, and pharmacotherapy.

Main Results:

  • LPR is linked to conditions such as vocal fold granulomas and subglottic stenosis.

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  • Diagnosis and treatment criteria for LPR remain subjects of ongoing debate.

    • Conclusions:

    • Optimal LPR management involves a multimodal approach combining lifestyle adjustments and high-dose proton pump inhibitors.
    • Allergists must be knowledgeable about LPR to effectively treat patients with refractory chronic cough and globus sensation.