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Updated: Aug 8, 2026

Purification of Pathogen Vacuoles from Legionella-infected Phagocytes
Published on: June 19, 2012
Domestic exposure to legionellae for Dutch Legionnaires' disease patients
Linda P B Verhoef1, Ed P F Yzerman, Jacob P Bruin
1Municipal Health Service Kennemerland Haarlem, The Netherlands. lpbverhoef@hdk.nl
Abstract:
The source of infection for travelers who develop Legionnaires' disease (LD) shortly after a journey abroad is difficult to ascertain. Infection is likely to have occurred abroad, but could also have occurred at the patient's own residence. The authors conducted a case-control study to determine risk for acquiring LD at home in the Netherlands after traveling abroad. They compared homes of 44 traveling LD patients with 44 homes of nontraveling LD patients, using logistic regression models. Geographic distribution was confounding the association between traveling and presence of Legionella spp. in residences; adjustment was necessary. In traveler's homes, legionellae were present more often, with crude and adjusted OR (95% CI) being 1.6 (0.5-5.0) and 1.4 (0.4-4.4), respectively. The authors' findings indicate that the patient's residence can be a potential source of infection after traveling.
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