Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cough motor mechanisms.

Giovanni A Fontana1, Federico Lavorini

  • 1Dipartimento di Area Critica Medico Chirurgica, Unità Funzionale di Medicina Respiratoria, Viale G.B. Morgagni 85, 50134 Firenze, Italy. g.fontana@dac.unifi.it

Respiratory Physiology & Neurobiology
|April 8, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Small Airways Disease Adversely Impacts the Response to Biologic Therapies in Severe Asthma.

Pulmonary therapy·2026
Same author

A Challenging Diagnosis of Hemophagocytic Lymphohistiocytosis with Unusual Pulmonary Manifestations: A Case Report.

The open respiratory medicine journal·2026
Same author

Integrating <i>In Vitro</i> Performance and <i>In Vivo</i> Patient-Reported Outcomes of a Mometasone Furoate Nasal Spray Device: A Translational Evaluation.

Journal of aerosol medicine and pulmonary drug delivery·2026
Same author

Factors associated with persistent symptoms after COVID-19 infection: a longitudinal study on an Italian cohort of patients discharged from hospital.

Infectious diseases (London, England)·2026
Same author

Tezepelumab in near-fatal asthma requiring VV-ECMO.

Respiratory medicine case reports·2026
Same author

Evaluation of short and long-term laboratory and instrumental findings in COVID-19 patients hospitalized in Tuscany.

World journal of experimental medicine·2026
Same journal

Physiological responses during a maximal dry static breath-hold in a world champion freediver.

Respiratory physiology & neurobiology·2026
Same journal

Intermittent Hypoxemia in Preterm Infants: Glial Fibrillary Acidic Protein as a Potential Brain Injury Biomarker.

Respiratory physiology & neurobiology·2026
Same journal

Asymmetry of thoracic expansion in hemiplegic stroke and its relationship with physical function and percent vital capacity: A cross-sectional study.

Respiratory physiology & neurobiology·2026
Same journal

Evaluating the shape of the expiratory flow volume curve in asymptomatic ex-smokers.

Respiratory physiology & neurobiology·2026
Same journal

Emphysema and airway disease synergistically impair exercise tolerance in smokers: A CT-based study.

Respiratory physiology & neurobiology·2026
Same journal

Oxygen extremes, inflammation, and neonatal breathing.

Respiratory physiology & neurobiology·2026
See all related articles

Cough involves primary and secondary motor mechanisms for airway defense. The exact function of some secondary cough responses, like breathing pattern changes, requires further investigation.

Area of Science:

  • Physiology
  • Neuroscience

Background:

  • Cough is a vital defensive reflex protecting the airways.
  • It involves a complex motor pattern primarily driven by laryngeal and respiratory muscles.
  • Additional 'secondary' motor responses also occur, potentially aiding defense or mitigating cough's side effects.

Purpose of the Study:

  • To elucidate the complex motor patterns of cough.
  • To differentiate between primary and secondary cough motor mechanisms.
  • To investigate the functional significance of secondary cough outflows, particularly breathing pattern changes.

Main Methods:

  • Analysis of the sequential activation of laryngeal and respiratory muscles during coughing.
  • Identification and categorization of primary and secondary cough motor responses.

Related Experiment Videos

  • Assessment of the functional roles and implications of these motor patterns.

    • Main Results:

    • Cough comprises a primary motor pattern and numerous secondary outflows.
    • Secondary outflows may enhance defense or counteract mechanical stress.
    • The functional meaning of some secondary responses, like altered breathing patterns, remains unclear.

    Conclusions:

    • Cough involves intricate primary and secondary motor mechanisms with diverse functions.
    • Further research is needed to fully understand the roles of all cough-related motor responses, especially volitional cough.
    • The functional significance of certain secondary cough responses requires elucidation.