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Updated: Jul 25, 2026

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
Case study: longitudinal treatment of adolescents with depression and inflammatory bowel disease
Eva Szigethy1, Johanna Carpenter, Emily Baum
1Department of Psychiatry, Children's Hospital Boston, MA, USA. szigethye@upmc.edu
Objective:
To assess longitudinal maintenance of improvements in depression, anxiety, global functioning, and physical health perception in 11 adolescents at 6 and 12 months following completion of manual-based cognitive-behavioral therapy.
Method:
Standardized instruments assessed follow-up changes in depression, anxiety, physical health, and global psychological functioning.
Results:
At both assessments, 10 adolescents did not meet criteria for mood disorders. Improvements in depression, anxiety, global functioning, and physical health perceptions at completion of the cognitive-behavioral therapy were maintained during the 12-month period. Additional cognitive-behavioral therapy sessions (mean = 4.36; SD = 4.37) and psychopharmacology (n = 5) were required during the follow-up period.
Conclusions:
CBT with maintenance sessions and medication offers promise to adolescents facing comorbid depressive and physical disorders.
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