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[Lymphadenopathy and constitutional symptoms. Progress of a low-grade follicular lymphoma?]
H J Stemmler1, M Hoelzl, N Moosmann
1Medizinische Klinik III, Klinikum Grosshadern der LMU München. joachim.stemmler@med.uni-muenchen.de
Abstract:
Atypical presentation of Churg-Strauss syndrome includes lymph-node and parenchymatous organ involvement which mimics the clinical presentation of lymphoproliferative disorders.A 54-year old man with a history of a low-grade follicular lymphoma presented with rapidly growing abdominal lymph-nodes and hepatic, renal and pulmonary infiltrations. CT guided biopsies to verify either lymphoma or infections showed eosinophilic, necrotizing, granulomatous vasculitis leading to the diagnosis of atypical Churg-Strauss syndrome. Within a few days of cyclophosphamide and prednisone treatment the clinical presentation improved and imaging studies detected regression of all manifestations during follow-up.
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