[Antioxidant vitamins status in patients with combined hyperlipidemia]

Diet can influence on the balance between antioxidants and prooxidants in the organism. The activity of enzymatic components of antioxidant system can be changed, the amount of harmful substances can be increased. The purpose of this study was to assess the effect of diet on vitamin A, E, C serum concentration in patients with combined hyperlipidemia. The studied group consisted of 38 subjects, aged 20-60 years. Dietary assessment was based on 24-h dietary recall. Serum lipids concentrations were assessed by enzymatic methods, serum vitamins concentrations were assessed by HPLC method. The energy intake in men was 2269.6 kcal, vitamin A consumption was 888.3 microg, vitamin E 8.7 mg and vitamin C 68.6 mg. In women energy intake was 2112 kcal, consumption of vitamin A was 580 mcirog, vitamin E 7.8 mg and vitamin C 68.6 mg. Only in 1 men deficient concentration of vitamin C was stated. Deficient concentration of vitamin A was not found but the desirable concentration was stated only in 5 men. The desirable vitamin E level was found only in men, not in women. The correlation between vitamin intake and its serum level was not observed. However, in women the correlations between intake of protein, dietary fiber, percentage of energy derived from fat and vitamin A serum level were found. To conclude, the serum concentration of antioxidant vitamins is determined by diet composition, adequate in energy and nutrients content.