Oxalate-containing phytocomplexes as dentine desensitisers: an in vitro study

Area of Science:

• Dentistry
• Biomaterials Science
• Pharmacognosy

Background:

• Dentinal hypersensitivity arises from pulpal fluid movement through dentinal tubules.
• Reducing fluid flow is a key strategy for alleviating dentinal hypersensitivity pain.

Purpose of the Study:

• To evaluate the efficacy of experimental phytocomplex substances containing oxalates in reducing dentinal permeability and altering dentinal morphology.
• To assess the acid resistance of these treatments.

Main Methods:

• Dentine discs from human molars were treated with experimental phytocomplexes (rhubarb, spinach, mint), a potassium oxalate paste, and commercial toothpastes.
• Treatments were applied via brushing, followed by an acid challenge (orthophosphoric acid).
• Dentinal permeability was measured, and morphology was analyzed using scanning electron microscopy.

Main Results:

• Phytocomplex treatments derived from spinach and rhubarb significantly reduced dentinal permeability.
• Occlusion of dentinal tubules was observed, attributed to the formation of calcium oxalate crystals.
• The treatments demonstrated varying degrees of resistance to acid challenge.

Conclusions:

• Phytocomplexes from rhubarb and spinach, in various formulations, are effective in occluding dentinal tubules.
• These natural compounds show potential as topical agents for treating dentinal hypersensitivity.