Singlet oxygen quantum yield determination for a fluorene-based two-photon photosensitizer
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Updated: Aug 9, 2026

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
Published on: February 7, 2022
Kevin D Belfield1, Mykhailo V Bondar, Olga V Przhonska
1Department of Chemistry and College of Optics and Photonics, CREOL and FPCE, University of Central Florida, P.O. Box 162366, Orlando, Florida 32816-2366, USA. kbelfiel@mail.ucf.edu
Abstract:
The quantum yield, Phi(Delta), of singlet oxygen generation under two-photon excitation has been determined for a fluorene derivative. A photochemical method was developed using 1,3-diphenylisobenzofuran (DPBF), a chemical quencher of 1O2, and 2-(9,9-didecyl-7-nitrofluoren-2-yl)benzothiazole (1) as a two-photon photosensitizer (PS). The photochemical kinetics of the quencher was measured by two different fluorescence methods. Fluorene 1 exhibited relatively high singlet oxygen quantum yield, Phi(Delta) approximately 0.4 +/- 0.1, and had a two-photon absorption cross-section of 28 +/- 5 GM. Thus, 1 may have potential for use as a two-photon PS in the near-IR spectral region for biomedical applications.
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