Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structure of DNA-CTAB-hexanol complexes.

Rema Krishnaswamy1, Georg Pabst, Michael Rappolt

  • 1Raman Research Institute, Bangalore 560 080, India.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|April 12, 2006
PubMed
Summary

DNA-cationic surfactant complexes show structural transitions with increasing hexanol. Low hexanol forms an intercalated hexagonal (HI) phase, while high hexanol forms an inverted hexagonal (HII) phase.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structural analysis of the lyotropic phases in alpha-olefin sulfonate as a function of water content and temperature.

Journal of colloid and interface science·2026
Same author

Dominant Role of Electron-Electron Scattering in the Photoinduced Terahertz Conductivity Spectra of Few-Layer WS<sub>2(1-<i>x</i>)</sub>Se<sub>2<i>x</i></sub> Flakes.

ACS nano·2026
Same author

Ten questions on membrane biophysics.

Biochimica et biophysica acta. Biomembranes·2026
Same author

Giant Helicity-Dependent Second Harmonic Generation in Type-2 Weyl Semimetal.

Physical review letters·2026
Same author

Reentrant melting of scarred odd crystals by self-shear.

Nature communications·2026
Same author

Origins of electrostriction of MoS<sub>2</sub> and HfS<sub>2</sub> in 2 and 3 dimensional 1T and 2H structures.

Nanoscale·2026

Area of Science:

  • Materials Science
  • Biophysics
  • Supramolecular Chemistry

Background:

  • Cationic surfactants like cetyltrimethylammonium bromide (CTAB) interact with DNA.
  • Cosurfactants can influence the self-assembly and phase behavior of surfactant-DNA complexes.
  • Understanding these structures is crucial for applications in gene delivery and materials science.

Purpose of the Study:

  • To investigate the structural phase transitions of DNA-CTAB complexes.
  • To determine the effect of hexanol concentration on the complex structures.
  • To characterize the different structural phases formed.

Main Methods:

  • Small-angle X-ray diffraction (SAXD) was employed to probe the complex structures.
  • Systematic variation of hexanol concentration was performed.

Related Experiment Videos

  • Quantitative analysis of diffraction data was conducted.

    • Main Results:

    • A structural transition from hexagonal to lamellar and back to hexagonal phases was observed with increasing hexanol content.
    • At low hexanol concentrations, an intercalated hexagonal (HI) structure was identified.
    • At higher hexanol concentrations, an inverted hexagonal (HII) structure was formed.

    Conclusions:

    • Hexanol acts as a cosurfactant, inducing significant structural rearrangements in DNA-CTAB complexes.
    • The observed phase transitions are dependent on the hexanol-to-surfactant ratio.
    • The study elucidates the formation of distinct hexagonal phases (HI and HII) in DNA-surfactant systems.