Related Experiment Video
Updated: Aug 9, 2026
06:07
Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Polymorphic light eruption may be associated with cigarette smoking and alcohol consumption
Greet Mentens1, Julien Lambert, Tamar Nijsten
1Department of Dermatology, University Hospital Antwerp, Edegem, Belgium.
Photodermatology, Photoimmunology & Photomedicine
|April 12, 2006
Summary
Lifestyle factors like smoking, alcohol, and oral contraceptive use may influence polymorphic light eruption (PLE). Heavy smoking and long-term oral contraceptive use were linked to PLE, while moderate alcohol consumption showed a protective effect.
Area of Science:
- Dermatology
- Epidemiology
Background:
- Genetic factors are known to influence polymorphic light eruption (PLE).
- The impact of lifestyle on PLE development requires further investigation.
Purpose of the Study:
- To investigate the association between lifestyle factors and polymorphic light eruption (PLE).
Main Methods:
- A retrospective case-control study involving 74 PLE patients and 102 controls.
- Data collected through interviews on demographics, disease history, and lifestyle (smoking, alcohol, medications).
- Multivariate logistic regression analysis to determine adjusted odds ratios (OR) and 95% confidence intervals (CI).
Main Results:
- PLE patients were more likely to be younger females.
- Smoking 15+ cigarettes daily was associated with a 4-fold increased likelihood of PLE.
- Consuming six or more alcoholic drinks weekly was associated with a decreased likelihood of PLE.
- Long-term oral contraceptive use in women increased PLE likelihood by four-fold.
Conclusions:
- Lifestyle factors including smoking, alcohol consumption, and oral contraceptive use may be associated with PLE.
- Further research is needed to validate these findings due to the retrospective nature of the study.
More Related Videos
Related Concept Videos
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
01:29Stimulants
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
01:26Stress Prevention and Stress Management Techniques IV
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
01:24Drug Toxicity: Risk factors
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
01:23Chronic Obstructive Pulmonary Disease II: Emphysema
Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
01:17Other Pulmonary Disorders
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.