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Accidental ingestion of Ecstasy in a toddler
Yi-Jung Chang1, Ming-Wei Lai, Man-Shan Kong
1Division of Pediatric Gastroenterology, Department of Pediatrics, Chang Gung Children's Hospital, Kwei-Shan, Taoyuan, Taiwan.
Insights
Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA), or Ecstasy, in toddlers can cause severe neurological and cardiovascular issues. Prompt supportive care is crucial for recovery, as demonstrated in a case of a 20-month-old child.
Area of Science:
- Pediatric Toxicology
- Emergency Medicine
- Pharmacology
Background:
- 3,4-methylenedioxymethamphetamine (MDMA), commonly known as Ecstasy, is a recreational drug with increasing incidence of abuse.
- Accidental ingestion in toddlers poses significant risks due to their vulnerability to its potent neurological and cardiovascular effects.
Observation:
- A 20-month-old male toddler presented with fever, seizures, tachycardia, hypertension, and hyperthermia after accidental Ecstasy ingestion.
- Initial assessment revealed a high urine amphetamine level (2111 ng/mL).
Findings:
- The toddler received supportive care, including rapid cooling and hydration.
- The patient's condition stabilized within 48 hours, with normalization of urine amphetamine levels by day 3.
- Full recovery was observed at outpatient follow-up, with the child returning to baseline behavior, activity, and appetite.
Implications:
- This case highlights the critical need to include accidental Ecstasy ingestion in the differential diagnosis for febrile seizures in toddlers.
- Increased awareness and prompt medical intervention are essential to manage pediatric MDMA toxicity effectively.
- Healthcare providers should be vigilant regarding the rising incidence of recreational drug abuse and its potential impact on child health.
Abstract:
Toddlers who ingest the drug of abuse 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') are at particularly high risk of serious neurological and cardiovascular side effects. We report of a 20-month-old male toddler who accidentally ingested Ecstasy. He presented with fever and seizures, tachycardia, hypertension, and hyperthermia. Urine amphetamine level was 2111 ng/mL. Treatment included rapid cooling, hydration, and support measures. Vital signs were regularly monitored. His condition became stable on day 2 and urine amphetamine level returned to normal on day 3 of hospitalization. His behavior, activity, and appetite had returned to their usual levels upon follow-up at our outpatient clinic. The incidence of drug abuse with MDMA has increased dramatically over the last decade in developed countries. It can be expected that accidental Ecstasy poisoning in children will increase as well. This case illustrates the need to consider the possibility of accidental Ecstasy ingestion in the differential diagnosis of a child suffering from convulsions with fever.
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