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Updated: Aug 9, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

[Oral modifications during menopause]

Maria Ursache1, Irina Grădinaru, Marie Jeanne Aldea

  • 1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină Dentară.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|April 13, 2006
PubMed

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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