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Updated: Aug 9, 2026
06:18
An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Oral modifications during menopause]
Maria Ursache1, Irina Grădinaru, Marie Jeanne Aldea
1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină Dentară.
Summary
Oral contraceptives may influence oral tissue changes during menopause. Women using oral contraceptives showed increased oral tissue changes compared to those who did not, highlighting the need for preventive oral health strategies.
Area of Science:
- Gerontology
- Oral Medicine
- Endocrinology
Background:
- Menopause is a physiological process in women over 50, marked by involutive phenomena affecting general health and the stomatognathic system.
- Oral health management in menopausal women requires understanding factors influencing oral tissue changes.
Purpose of the Study:
- To investigate the influence of past oral contraceptive use on oral tissue changes in menopausal women.
- To compare oral tissue health between menopausal women with and without a history of oral contraceptive therapy.
Main Methods:
- A study involving 148 menopausal women, divided into a group with prior oral contraceptive use (Group I) and a control group without (Group II).
- Evaluations included clinical examinations, X-rays, cytological, histopathological, mycological, and salivary rate assessments, along with index quantification.
Main Results:
- Menopausal women with a history of oral contraceptive use exhibited a greater incidence and severity of changes in oral tissues compared to the control group.
- Significant differences were observed in various oral tissue parameters between the two groups.
Conclusions:
- Past oral contraceptive use appears to be associated with increased oral tissue alterations during menopause.
- Targeted prevention strategies are crucial for optimizing oral health in women experiencing menopause.
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