Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Meropenem activity against staphylococci].

Antonia Poiată1, Cristina Tuchiluş, Andreea Costea

  • 1Universitatea de Medicină şi Farmacie Gr T Popa Iaşi, Facultatea de Farmacie, Disciplina de Microbiologie.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|April 13, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating GDF-15 into Multimarker Assessment of Acute Heart Failure: Diagnostic and Prognostic Implications.

Life (Basel, Switzerland)·2026
Same author

Can Endothelin-1 Help Address the Diagnostic and Prognostic Challenges in Multimorbid Acute Heart Failure Patients?

Life (Basel, Switzerland)·2025
Same author

The First Report of <i>mcr</i>-1-Carrying <i>Escherichia coli</i>, Isolated from a Clinical Sample in the North-East of Romania.

Microorganisms·2025
Same author

Insights into Catechin-Copper Complex Structure and Biologic Activity Modulation.

Molecules (Basel, Switzerland)·2024
Same author

Discovery of new molecular hybrid derivatives with coumarin scaffold bearing pyrazole/oxadiazole moieties: Molecular docking, POM analyses, in silico pharmacokinetics and in vitro antimicrobial evaluation with identification of potent antitumor pharmacophore sites.

Bioorganic chemistry·2024
Same author

Development of cream bases suitable for personalized cosmetic products.

Medicine and pharmacy reports·2024

Meropenem demonstrates superior antimicrobial activity against staphylococci compared to other antibiotics. This new carbapenem exhibited zero resistance in all tested strains, highlighting its potential effectiveness.

Area of Science:

  • Microbiology
  • Pharmacology
  • Infectious Diseases

Background:

  • Meropenem is a carbapenem antibiotic known for broad-spectrum activity.
  • Its efficacy is linked to resistance against bacterial beta-lactamases.
  • Staphylococci are common bacteria that can cause various infections.

Purpose of the Study:

  • To evaluate the antimicrobial activity of meropenem.
  • To compare meropenem's efficacy against oxacillin, gentamicin, clarithromycin, and ciprofloxacin.
  • To assess meropenem's activity against staphylococcal strains.

Main Methods:

  • Agar dilution technique was used to determine Minimum Inhibitory Concentrations (MICs).
  • 458 staphylococcal strains collected from healthy individuals in 2004 were tested.

Related Experiment Videos

  • Comparative analysis of meropenem versus four other antibiotics was performed.

    • Main Results:

    • Meropenem showed significantly superior antimicrobial activity compared to oxacillin, gentamicin, clarithromycin, and ciprofloxacin.
    • No resistance to meropenem was observed in any of the 458 staphylococcal strains.
    • Meropenem's effectiveness was clearly demonstrated across all tested staphylococci.

    Conclusions:

    • Meropenem exhibits excellent activity against staphylococci.
    • The study supports meropenem as a highly effective agent against staphylococcal infections.
    • Meropenem presents a zero resistance rate, indicating its robust antibacterial profile.