Related Experiment Videos
Cellular retinoic acid-binding protein in rat lacrimal gland
K Yamaguchi1, V P Gaur, R W Young
1Department of Ophthalmology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157.
Investigative Ophthalmology & Visual Science
|December 1, 1991
Abstract:
We employed a monoclonal antibody to cellular retinoic acid-binding protein (CRABP) to assess the presence and localization of this retinoid-binding protein in the lacrimal gland of the rat. Immunoblots of extracts of rat lacrimal gland showed specific immunostaining of lacrimal CRABP in the region 14-16 kDa. Sections of rat lacrimal glands that were stained with anti-CRABP antibodies showed reaction product in the cytoplasm of the acinar cells. Retinoic acid may play a role in maintaining the proper function of lacrimal gland cells.