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Updated: Aug 9, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Death of a president and his assassin--errors in their diagnosis and autopsies
1The Ohio State University, Institute for Collaborative Research and Public Humanities, Columbus, Ohio 43201-1654, USA. paulson.2@osu.edu
Abstract:
On July 2, 1881, Charles Julius Guiteau shot President James Abram Garfield in the right flank. The President died because of infection produced by the unsterile fingers and probes repeatedly inserted into the wound. The major complaint of the wounded President was intractable pain in his legs and feet. This symptom failed to alert the doctors to the possibility of vertebral and spinal cord injury. Garfield died with sepsis after 80 days of intense national concern, and for the patient there was psychological, physical, and nutritional deprivation. His autopsy revealed the bullet was not in the pelvis as his doctors had expected, but adjacent to the first lumbar vertebra it had shattered. The trial and execution of Guiteau split the medical community into those that considered him insane and those who felt execution was justified. Guiteau was delusional and his brain revealed chronic inflammation and histological features suggestive of syphilis. At the time, and since, the propriety of the execution has been questioned.
Insights
President James Garfield
Area of Science:
- Medical History
- Forensic Pathology
- Infectious Disease
Background:
- Details the assassination of President James A. Garfield on July 2, 1881, by Charles Julius Guiteau.
- Highlights the fatal role of unsterile medical practices and infection in President Garfield's death.
- Notes the President's leg pain, which was overlooked as a potential indicator of spinal injury.
Discussion:
- Examines the autopsy findings, revealing the bullet's location near the shattered first lumbar vertebra, not the pelvis.
- Discusses the medical community's division regarding Guiteau's sanity and the justification of his execution.
- Considers Guiteau's documented delusions and pathological brain findings suggestive of chronic inflammation and syphilis.
Key Insights:
- President Garfield died from sepsis due to complications from unsterile medical interventions, not solely the gunshot wound.
- The overlooked symptom of leg pain may have indicated a critical vertebral and spinal cord injury.
- Guiteau's mental state and the ethical implications of his execution remain subjects of historical debate.
Outlook:
- This case underscores the critical importance of sterile techniques in medical practice.
- It highlights the need for comprehensive diagnostic approaches, considering all symptoms, especially in complex trauma cases.
- The historical analysis of the assassination and trial offers insights into past medical understanding and legal-psychiatric evaluations.
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