Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stem cells and kidney injury.

Cecile Vigneau1, Feng Zheng, Katalin Polgar

  • 1Mount Sinai School of Medicine, Department of Medicine, New York, New York 10029, USA.

Current Opinion in Nephrology and Hypertension
|April 13, 2006
PubMed
Summary

Regenerative nephrology is emerging, with stem cell therapy showing promise. Both embryonic and adult stem cells, particularly those from bone marrow, may offer new therapeutic avenues for kidney repair and regeneration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The epidemiology of end-stage kidney failure in France: reason for hope?

Clinical kidney journal·2026
Same author

Chronic kidney disease stage 4 and 5: comparison of therapeutic projects before kidney replacement therapy between men and women in Brittany.

Journal of nephrology·2026
Same author

Children born to mothers receiving chronic dialysis, a national French cohort (2013-2021).

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Evolution of the psychological repercussions of the COVID-19 pandemic on hemodialysis patients and caregivers between April 2020 and April 2022

Nephrologie & therapeutique·2025
Same author

Nephrologists' perception of the French national guidelines in nephrology.

Scientific reports·2025
Same author

Optimizing ADAMTS13 prophylaxis to reduce relapse and organ failure in congenital thrombotic thrombocytopenic purpura.

Blood advances·2025

Area of Science:

  • Nephrology
  • Regenerative Medicine
  • Stem Cell Biology

Background:

  • Current nephrology therapies focus on managing kidney injury, slowing disease progression, and renal replacement.
  • Stem cells, characterized by self-renewal and multilineage differentiation, are classified as embryonic or adult.
  • The potential of renal progenitors for therapeutic applications is an area of active investigation.

Purpose of the Study:

  • To review emerging evidence on the therapeutic potential of renal progenitors.
  • To explore the role of stem cells in regenerative nephrology.

Main Methods:

  • Review of recent studies on embryonic stem cells (ESCs) and adult stem cells (ASCs).
  • Analysis of research investigating stem cell integration into renal structures.

Related Experiment Videos

  • Examination of animal studies on stem cell-mediated phenotype transfer.

    • Main Results:

    • Embryonic stem cells can be directed to enrich specific renal progenitors that integrate into mature kidney structures.
    • Adult stem cells, particularly from bone marrow, demonstrate the capacity to renew nearly all kidney cell types.
    • Animal studies suggest bone marrow progenitors may transfer phenotypes, including aging and diabetic traits, indicating therapeutic potential.

    Conclusions:

    • Stem cell therapy represents a significant advancement towards regenerative nephrology.
    • Embryonic stem cells are valuable for elucidating pathways to renal progenitor development.
    • Adult stem cells from bone marrow or kidney niches hold therapeutic promise for kidney regeneration.