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Updated: Aug 9, 2026
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
[Differenciated thyroid carcinomas with laryngo-tracheal invasion]
J Miloundja1, E Lescanne, B Ouedraogo
1Service d'ORL et de chirurgie cervico-faciale, Hôpital Bretonneau, CHU de Tours.
Summary
Differentiated thyroid carcinomas invading the larynx and trachea have higher recurrence rates. Surgical management aims for complete tumor removal while preserving laryngeal function.
Area of Science:
- Oncology
- Otorhinolaryngology
- Head and Neck Surgery
Background:
- Differentiated thyroid carcinoma (DTC) can invade adjacent laryngeal and tracheal structures.
- Laryngo-tracheal invasion in DTC presents unique diagnostic and therapeutic challenges.
Purpose of the Study:
- To analyze the diagnosis and treatment strategies for DTC with laryngo-tracheal invasion.
- To evaluate surgical outcomes and recurrence rates in these specific cases.
Main Methods:
- Retrospective study of seven patients with DTC and laryngo-tracheal invasion treated between 1990 and 2003.
- Surgical interventions included various laryngo-tracheal resections and thyroid cartilage procedures.
Main Results:
- Surgical procedures varied, from thyroid cartilage shaving to total laryngectomy.
- Complications included swallowing disorders, hypoparathyroidism, recurrent nerve paralysis, and Horner's syndrome.
- Locoregional recurrences and distant metastases occurred in 2 patients each, with a mean follow-up of 40 months.
Conclusions:
- DTC with laryngo-tracheal invasion demonstrates a higher frequency of locoregional recurrences and distant metastases.
- Surgical goals prioritize macroscopic carcinological clearance while maximally preserving laryngeal function.
