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Osteoporosis in liver cirrhosis--overview
Cristina Cijevschi1, Cătălina Mihai, V L Drug
1Gastroenterology and Hepatology Institute Iaşi, "Gr.T. Popa" University of Medicine and Pharmacy, Iaşi.
Abstract:
Osteoporosis can occur as a result of liver cirrhosis. The pathogenesis of reduced bone mineral density in liver cirrhosis is multifactorial. It can be caused by alterations in calcium and vitamin D homeostasis, as well as nutritional and dietary factors. Dual-energy X-ray absorptiometry (DXA) has become the gold standard in assessing bone mineral density in patients with liver cirrhosis. In such cases, patients can be treated with calcium and vitamin D supplements, bisphosphonates and hormonal replacement therapy (HRT).
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