Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acute gastrointestinal bleeding: Part I.

D Collins1, L I Worthley

  • 1Department of Critical Care Medicine, Flinders Medical Centre, Adelaide, SA, Australia.

Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine
|April 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Asymptomatic thrombocytopenia in Akitas: a prospective cross-sectional study of platelet characteristics in an Eastern Australian population.

Australian veterinary journal·2026
Same author

Ocular involvement in toxic epidermal necrolysis syndrome at Chelsea and Westminster Hospital: a 10-year retrospective analysis and review of current literature.

Eye (London, England)·2026
Same author

All-cause mortality rates in nonagenarians treated for hip fracture.

Irish medical journal·2026
Same author

Microscale-patterned SERS substrates with exceptional uniformity: Addressing reproducibility challenges.

Talanta·2026
Same author

Charge acceleration without radiation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting.

Cancers·2025
Same journal

A pragmatic risk-stratified framework for using large language models in intensive care medicine: A narrative review.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same journal

The cost analysis of remifentanil and fentanyl for analgosedation in mechanically ventilated patients in intensive care: Post hoc analysis of an open-labelled pilot randomised controlled study.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same journal

Analgesia and sedation practice in children in intensive care in Australia and New Zealand: A survey.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same journal

Evaluation of the clinical impact of different telemedicine practices in intensive care units: A stepped-wedge cluster randomized clinical trial (TELESCOPE 2): Study protocol.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same journal

Vasopressors or fluids for initial resuscitation in septic shock: A matter of clinical judgement.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same journal

Sodium bicarbonate in critical illness: Correcting acidaemia without changing outcomes?

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
See all related articles

Critical care patients with gastrointestinal bleeding often receive intravenous proton pump inhibitors and endoscopic treatment. For lower GI bleeding, angiography with embolization is an alternative to surgery, with fibrinolytic inhibitors potentially aiding treatment.

Area of Science:

  • Critical care medicine
  • Gastroenterology
  • Emergency medicine

Background:

  • Acute gastrointestinal bleeding is a frequent complication in critically ill patients.
  • Common causes include acute stress ulceration, peptic ulceration, and esophageal varices.

Purpose of the Study:

  • To review the management strategies for acute gastrointestinal bleeding in critically ill patients.
  • To provide an overview of current treatment options based on a literature review.

Main Methods:

  • A MEDLINE search of English-language literature from 1991 to 2001.
  • Review of articles and studies on acute gastrointestinal bleeding in critically ill patients.

Main Results:

  • Upper GI bleeding management involves resuscitation, coagulation correction, endoscopy, and often proton pump inhibitors (PPIs) and endoscopic interventions like adrenaline injection or electrocautery.

Related Experiment Videos

  • PPIs are preferred over H2 receptor antagonists for acute stress ulceration due to superior acid suppression.
  • For severe bleeding, fibrinolytic inhibitors may be beneficial.
  • Lower GI bleeding or unidentified upper GI sources may be managed with selective mesenteric angiography and embolization or colonoscopy with interventions.

    • Conclusions:

    • Intravenous PPIs and endoscopic interventions are primary treatments for acute upper GI bleeding in critically ill patients.
    • Selective mesenteric angiography with embolization offers a surgical alternative for lower GI hemorrhage.
    • Fibrinolytic inhibitors can provide additional benefits in managing severe bleeding.