Pregnancy outcome among twins conceived after subfertility treatment compared with natural twins: A population-based
Michael F G Murphy1, Rachel E Neale, Kate Hey
1Childhood Cancer Research Group, University of Oxford Department of Pediatrics, Oxford, United Kingdom. michael.murphy@ccrg.oxford.ac.uk
Abstract:
Pregnancy outcome and characteristics of women who conceive following subfertility treatment remains a subject of great interest. We analyzed these variables among 199 women who delivered a registerable twin birth compared with 1773 women who delivered a naturally conceived twin birth in a population-based obstetric cohort drawn from around Oxford, England. Treatment was restricted to conceptions involving simple ovulation induction only. Treated mothers were of significantly higher social class and older, more likely to deliver girls and to be delivered by cesarean section, and significantly less likely to be smokers at the time of antenatal booking and to have delivered previous pregnancies. Pregnancy outcome was similar between the two groups for most measures, with the exception of birthweight which was lower in treated twins, though not significantly so. Overall the results are reassuring with respect to outcome in twin pregnancies following simple ovulation induction.
Related Concept Videos
Regression Toward the Mean
Ovarian Cycle
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Infertility in Males
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of endometrial...
