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The rab exchange factor Sec2p reversibly associates with the exocyst

Martina Medkova1, Y Ellen France, Jeff Coleman

  • 1Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.

Molecular Biology of the Cell
|April 14, 2006
PubMed
Summary

Sec2p, a regulator of secretory vesicle transport, binds to the exocyst complex via Sec15p. This interaction is crucial for vesicle exocytosis and recycling, with mutations disrupting release and causing vesicle accumulation.

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