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Updated: Aug 9, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
[Aortic root enlargement in elderly patients]
1Department of Cardiovascular Surgery, Tohoku Kosai Hospital, Sendai, Japan.
Aortic root enlargement (ARE) using the Nicks procedure is a safe and effective treatment for elderly patients with severe aortic stenosis and small aortic annulus, showing significant improvements in heart function and reduced ventricular mass.
Area of Science:
- Cardiovascular Surgery
- Geriatric Cardiology
- Cardiac Valve Disease
Context:
- Severe aortic stenosis poses significant risks, especially in elderly patients.
- The small aortic annulus in elderly patients presents surgical challenges.
- The Nicks procedure offers a potential solution for aortic root enlargement (ARE).
Purpose:
- To evaluate the safety and efficacy of the Nicks procedure for aortic root enlargement (ARE) in elderly patients with severe aortic stenosis.
- To assess the impact of ARE on cardiac function, ventricular mass, and clinical outcomes.
- To compare ARE alone versus combined procedures in this patient population.
Summary:
- Twelve elderly patients (mean age 79.3) with severe aortic stenosis underwent ARE using the Nicks procedure.
- No deaths occurred; significant improvements were observed in cardiothoracic ratio, NYHA functional class, peak pressure gradient, and left ventricular mass index (LVMI).
- ARE alone showed a favorable safety profile compared to combined procedures, with comparable echocardiographic results.
Impact:
- The Nicks procedure is a safe and effective option for elderly patients with severe aortic stenosis and small aortic annulus when performed without concomitant procedures.
- Demonstrates significant regression of left ventricular mass and improvement in cardiac function post-operatively.
- Highlights the importance of considering ARE as a standalone procedure to minimize risks in this vulnerable population.
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