Related Experiment Video
Updated: Aug 9, 2026

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
Published on: November 25, 2025
[Dealing with medically unexplained symptoms in general practice: from irritation to 'the tricks of the trade']
1Erasmus MC, afd. Huisartsgeneeskunde, Dr. Molewaterplein 50, 3015 GE Rotterdam. s.thomas@erasmusmc.nl
Abstract:
Patients with medically unexplained symptoms pose a problem for medical professionals. Doctors usually lack tools to handle these complaints adequately. Over the past decades much research has been done in the areas of classification and intervention both in general practice and in specialist care. If the doctor responds to the patient by offering to prescribe medicinal symptom relief, the first step into the vicious circle is taken. The patient is polite enough to try the medication but when it does not help, returns to the doctor. If the doctor continues to think along somatic lines the phenomenon known as iatrogenically enforced somatic fixation may arise. The main development in intervention stems from cognitive behavioural therapy, which is now considered the gold standard for all patients, regardless of their symptoms. In the Netherlands, a postgraduate course has been developed to implement the fundamentals of this approach into general practice. On this course, the doctor learns not to be deterred by the somatizing patient and to effectively close off their somatic treatment trajectory. He or she teaches the patient to look at the situation from a new perspective and instead of being preoccupied with what is not functioning well to concentrate on training those activities which can be carried out effectively. This shift in emphasis can help to cause the preoccupation of the patient to slowly disappear. Initial results are encouraging: both patients and general practitioners have responded favourably.
Related Concept Videos
Irritable Bowel Syndrome III: Medical and Nursing Management
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Irritable Bowel Syndrome

