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Updated: Aug 9, 2026

Quantifying the Binding Interactions Between Cu(II) and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
Properties of the copper(II)-histidine complex obtained after dialysis of human plasma with histidine
Tony Venelinov1, Sonia Arpadjan, Irina Karadjova
1Sofia University, Faculty of Chemistry, Department of Analytical Chemistry, 1164 Sofia, Bulgaria. SGaneva@chem.uni-sofia.bg
Abstract:
The copper(II)-histidine complex obtained following dialysis of human plasma with histidine was investigated using various types of extraction systems and ion exchange resins. According to the results obtained, the Cu(II)-histidine complex formed under the dialysis conditions has one positive charge. Preconcentration of copper from the dialysis solution was achieved by its extraction as a dithiocarbamate complex and by sorption on cation-exchange resin or onto chelate sorbent.
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