Notch signaling is inactive but inducible in human embryonic stem cells

Scott A Noggle1, Deborah Weiler, Brian G Condie

  • 1Department of Genetics, University of Georgia, Davison Life Sciences Complex, Athens, 30602, USA.

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The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
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