Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experimental bladder carcinogenesis-rodent models.

P A Oliveira1, A Colaco, L F De la Cruz P

  • 1Department of Veterinary Sciences, CECAV, University of Tras-os-Montes and Alto Douro, Vila Real, Portugal. pamo@utad.pt

Experimental Oncology
|April 15, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the knowledge, attitudes, and practices of livestock veterinarians on antibiotic prescription and use: insights from focus group discussions.

Animal : an international journal of animal bioscience·2025
Same author

Comparative study of the quality of breast meat of free-range chicken (Gallus gallus domesticus) and conventional chicken (Gallus gallus).

Brazilian journal of biology = Revista brasleira de biologia·2024
Same author

Using a food web model to predict the effects of Hazardous and Noxious Substances (HNS) accidental spills on deep-sea hydrothermal vents from the Mid-Atlantic Ridge (MAR) region.

Marine pollution bulletin·2024
Same author

Optimizing the use of systemic corticosteroids in severe asthma (ROSA II project): a national Delphi consensus study.

Pulmonology·2023
Same author

SKELETAL MUSCLE SENSITIVITY TO WASTING INDUCED BY UROTHELIAL CARCINOMA.

Experimental oncology·2023
Same author

Mepolizumab in severe asthma exacerbation in a respiratory ICU-a successful off-label use.

Pulmonology·2023
Same journal

Polyfunctional Thiazole/Thiazolidinone Derivatives as a New Class of Heterocyclic Compounds with Novel Mechanisms of Anticancer Activity.

Experimental oncology·2026
Same journal

Metabolic Inhibitors and their Impact on Cancer Cell Migration, Invasion, and Metastasis.

Experimental oncology·2026
Same journal

Changes in Cytokine Profile of Macrophages Induced by Chronic Stress in intact and tumor-bearing rats.

Experimental oncology·2026
Same journal

Integrated Analysis of hsa-miR-26b-5p and hsa-miR-186-5p in Blood Serum and Tumor Tissue Reveals their Prognostic and Predictive Significance in Breast Cancer.

Experimental oncology·2026
Same journal

FNBP1 in Chronic Myeloid Leukemia: Spatial Association with BCR-ABL and Potential Implications for Targeted Therapy.

Experimental oncology·2026
Same journal

Stress-Induced Changes in the Methylation Status of Mmp1 and Mmp8 Genes in Tumor Tissue of Rats with Guerin Carcinoma.

Experimental oncology·2026
See all related articles

This review assesses rodent models for bladder cancer research, covering chemical carcinogens, implantation methods, and irradiation. Choosing the right model is crucial for studying bladder cancer development, prevention, and therapy.

Area of Science:

  • Oncology
  • Comparative Medicine
  • Toxicology

Background:

  • Rodent models are essential for studying bladder cancer.
  • Various methods exist to induce or study bladder tumors in animals.
  • Selecting an appropriate model significantly impacts research outcomes.

Purpose of the Study:

  • To critically evaluate diverse animal models for bladder cancer research.
  • To assess models for studying bladder cancer development, chemoprevention, and therapy.
  • To provide insights into selecting suitable models for bladder carcinogenesis studies.

Main Methods:

  • Review of established rodent models for bladder cancer.
  • Description of chemical carcinogens, implantation techniques, and irradiation.

Related Experiment Videos

  • Evaluation of cell cultures, tumor implantation, and transgenic models.
  • Assessment of imaging techniques for studying rodent bladder carcinogenesis.

    • Main Results:

    • Most models, excluding transgenic and knockout, require 8-12 months for tumor development.
    • Spontaneous bladder tumor models are rare.
    • The choice of model is critical and benefits from comparative medical knowledge.

    Conclusions:

    • A comprehensive understanding of available models is vital for effective bladder cancer research.
    • Diverse tools, including chemical induction, implantation, and genetic models, aid in studying bladder carcinogenesis.
    • Imaging techniques offer valuable applications in monitoring rodent bladder cancer progression.