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Related Experiment Videos

Imaging in urinary tract infection.

F V Gleeson1, I Gordon

  • 1Imaging Department, Hospital for Sick Children, London.

Archives of Disease in Childhood
|November 1, 1991
PubMed
Summary
This summary is machine-generated.

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Vesicoureteric reflux (VUR) and renal scarring in children with urinary tract infections show a strong link. However, VUR detection poorly correlates with scarring in children over one year old, suggesting kidney imaging first.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Diagnostic Imaging

Background:

  • Urinary tract infections (UTIs) are common in children.
  • Vesicoureteric reflux (VUR) and renal scarring are significant concerns following UTIs.
  • The diagnostic approach to identify these conditions is crucial for preventing long-term kidney damage.

Purpose of the Study:

  • To investigate the relationship between VUR and renal scarring in children with UTIs.
  • To evaluate the diagnostic utility of DMSA scans and cystograms in different age groups.
  • To determine the optimal imaging strategy for children presenting with UTIs.

Main Methods:

  • A cohort of 94 children (188 kidneys) with confirmed UTIs were studied.
  • All participants underwent a micturating cystourethrogram (MCU) and a 99mTc DMSA scan.

Related Experiment Videos

  • Data on VUR, renal scarring, and patient age were collected and analyzed.
  • Main Results:

    • Of 188 kidneys, 42 showed scarring and 70 had VUR.
    • Scarring was present in 37.1% of kidneys with VUR, while 61.9% of scarred kidneys had VUR.
    • In children over 1 year, VUR detection showed a poor correlation with renal scarring.

    Conclusions:

    • A strong correlation exists between DMSA-detected renal scarring and the presence of VUR.
    • In children over one year old with UTIs, DMSA scans should be the primary imaging modality.
    • Cystograms should be reserved for cases where the DMSA scan reveals abnormalities, optimizing diagnostic pathways.