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Targeted therapies: a nursing perspective

Polly Kay1

  • 1UCLA Clinical Research Unit, University of California-Los Angeles, 10945 Le Conte Avenue, PVUB 3360, Los Angeles, CA 90095, USA. pkay@mednet.ucla.edu

Seminars in Oncology Nursing
|April 18, 2006
PubMed
Abstract

Insights

Targeted therapies offer more specific cancer cell action and better tolerability than traditional chemotherapy. These advancements expand treatment options, particularly for patients resistant to chemotherapy.

Area of Science:

  • Oncology
  • Pharmacology
  • Cancer Biology

Background:

  • Review of targeted therapy development and relevant biological targets.
  • Analysis of targeted agents in current clinical oncology practice.

Purpose of the Study:

  • To examine the evolution of targeted cancer therapies.
  • To assess the clinical utility and impact of targeted agents.

Main Methods:

  • Systematic review of research articles.
  • Analysis of preclinical and clinical data on targeted agents.

Main Results:

  • Multiple targeted agents are clinically available, offering specific mechanisms against tumor cells.
  • Targeted therapies demonstrate improved tolerability in monotherapy and feasibility in combination regimens.
  • Expanded cancer treatment options, especially for refractory cases.

Conclusions:

  • Targeted therapies represent a significant advancement in cancer treatment.
  • Enhanced understanding of targeted therapies is crucial for oncology nurses.
  • Knowledge of mechanisms, efficacy, adverse events, and administration is vital for nursing practice.

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