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Targeted therapies: a nursing perspective.

Polly Kay1

  • 1UCLA Clinical Research Unit, University of California-Los Angeles, 10945 Le Conte Avenue, PVUB 3360, Los Angeles, CA 90095, USA. pkay@mednet.ucla.edu

Seminars in Oncology Nursing
|April 18, 2006
PubMed
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Targeted therapies offer more specific cancer cell action and better tolerability than traditional chemotherapy. These advancements expand treatment options, particularly for patients resistant to chemotherapy.

Area of Science:

  • Oncology
  • Pharmacology
  • Cancer Biology

Background:

  • Review of targeted therapy development and relevant biological targets.
  • Analysis of targeted agents in current clinical oncology practice.

Purpose of the Study:

  • To examine the evolution of targeted cancer therapies.
  • To assess the clinical utility and impact of targeted agents.

Main Methods:

  • Systematic review of research articles.
  • Analysis of preclinical and clinical data on targeted agents.

Main Results:

  • Multiple targeted agents are clinically available, offering specific mechanisms against tumor cells.
  • Targeted therapies demonstrate improved tolerability in monotherapy and feasibility in combination regimens.

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  • Expanded cancer treatment options, especially for refractory cases.

    • Conclusions:

    • Targeted therapies represent a significant advancement in cancer treatment.
    • Enhanced understanding of targeted therapies is crucial for oncology nurses.
    • Knowledge of mechanisms, efficacy, adverse events, and administration is vital for nursing practice.