Related Experiment Video

Updated: Jun 20, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

[The pathogens of atypical respiratory infections and asthma]

Romuald Carewicz1, Andrzej Chciałowski

  • 1Wojskowy Instytut Medyczny w Warszawie, Klinika Chorób Wewnetrznych, Pneumonologii i Alergologii CSK MON. carewicz@neostrada.pl

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|April 19, 2006
PubMed

Insights

Atypical respiratory pathogens like Mycoplasma pneumoniae and Chlamydia pneumoniae can worsen asthma. Their exact role in asthma development and potential protective effects require further investigation.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pulmonology

Context:

  • Atypical respiratory pathogens represent a diverse group of microorganisms.
  • Classical atypical pathogens include bacteria such as Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila.
  • This group also encompasses certain viruses and rickettsia.

Purpose:

  • To explore the multifaceted role of atypical respiratory infections in asthma.
  • To discuss their involvement in asthma exacerbations and potential contribution to asthma development.
  • To examine speculative protective effects against atopy and asthma.

Summary:

  • Atypical pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila, viruses, and rickettsia, are implicated in respiratory health.
  • These infections are frequently associated with exacerbations of asthma.
  • Their precise role in the development of asthma and any potential protective effects remain subjects of ongoing research and discussion.

Impact:

  • Highlights the complex relationship between atypical infections and asthma.
  • Underscores the need for further research to clarify the etiological and prognostic significance of these pathogens in asthma.
  • Informs clinical understanding and management strategies for patients with asthma and atypical respiratory infections.

More Related Videos

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy10:39

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

Assessing Respiratory Immune Responses to Haemophilus Influenzae06:32

Assessing Respiratory Immune Responses to Haemophilus Influenzae

Published on: June 29, 2021

Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...