Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Warfarin-induced gastric bleeding and intestinal obstruction.

Nimrod Maimon1, Todd Penner, Wilfred Demajo

  • 1Division of Respirology, Department of Medicine, Western Hospital, University Health Network, University of Toronto, 1 King's College Circle, Rm 6263 MSB, Toronto, ON, Canada M5S 1A8.

European Journal of Internal Medicine
|April 19, 2006
PubMed
Summary

Warfarin therapy can rarely cause internal bleeding, leading to a life-threatening bowel obstruction. This case highlights an unusual complication of anticoagulant treatment requiring surgical intervention.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimating the odds ratio from the output scores of machine learning models: possibilities and limitations.

Scientific reports·2026
Same author

[Special considerations in bariatric surgery].

Orvosi hetilap·2025
Same author

Fatal pulmonary <i>Mycobacterium xenopi</i> in a patient with rheumatoid arthritis receiving etanercept.

BMJ case reports·2025
Same author

Development of saliva-based cardiac troponin I point-of-care test using alpha-amylase depletion: a feasibility study.

Coronary artery disease·2023
Same author

National Weekly SARS-CoV-2 RT-PCR Screening of All Workers in Long-Term Care Facilities Associated with Decrease in Resident Mortality Rate.

Gerontology·2023
Same author

Comparison of Rate Control Efficacy between beta-blockers and Calcium Channel Blockers in Patients Hospitalized with Atrial Fibrillation.

The Israel Medical Association journal : IMAJ·2022

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Surgical Oncology

Background:

  • Oral anticoagulants like warfarin are crucial for preventing thromboembolic events.
  • Warfarin therapy requires frequent monitoring due to variable patient responses and bleeding risks.
  • Excessive anticoagulation is directly linked to an increased risk of bleeding complications.

Purpose of the Study:

  • To report a rare case of warfarin-induced intraluminal hematoma causing mechanical ileus.
  • To highlight a potentially lethal, previously undescribed manifestation of warfarin therapy.

Main Methods:

  • A patient presented with acute abdomen, anemia, and elevated international normalized ratio (INR).
  • Diagnostic procedures included gastroscopy and laparotomy.

Related Experiment Videos

  • Surgical intervention involved evacuating an intraluminal hematoma.

    • Main Results:

    • Gastroscopy revealed significant gastric hemorrhage.
    • Laparotomy identified ischemic small bowel secondary to increased intraluminal pressure from a hematoma.
    • Evacuation of the hematoma restored intestinal blood supply.

    Conclusions:

    • Intraluminal hematoma is a rare cause of obstructive mechanical ileus in patients on warfarin.
    • This case expands the spectrum of known warfarin-related complications.
    • Early recognition and surgical management are critical for this potentially fatal condition.