Acute interstitial nephritis associated with salmonellosis

Jo Caers1, Patrick Peeters, Kaat Vanden Houte

  • 1Department of Internal Medicine, Academic Hospital-Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium.

Insights

Acute interstitial nephritis (AIN), a cause of kidney failure, can be triggered by Salmonella infections. This rare complication, confirmed by biopsy, suggests Salmonella should be considered in AIN cases.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Pathology

Background:

  • Acute interstitial nephritis (AIN) is a significant cause of acute kidney injury.
  • Salmonella infections are typically associated with gastrointestinal illness.
  • AIN as a complication of Salmonella is exceptionally rare in medical literature.

Purpose of the Study:

  • To report a case of AIN secondary to Salmonella hadar infection.
  • To highlight the potential for Salmonella to cause AIN.
  • To contribute to the understanding of rare AIN etiologies.

Main Methods:

  • Case report of a patient with typhoid fever.
  • Confirmation of AIN through renal biopsy.
  • Identification of Salmonella hadar as the causative agent.

Main Results:

  • The patient presented with AIN.
  • Renal biopsy confirmed interstitial nephritis.
  • The AIN was attributed to Salmonella hadar infection.

Conclusions:

  • Salmonella infection can cause acute interstitial nephritis.
  • This case represents a rare instance of AIN secondary to Salmonella.
  • Salmonella should be included in the differential diagnosis for AIN.

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