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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Acute interstitial nephritis associated with salmonellosis
Jo Caers1, Patrick Peeters, Kaat Vanden Houte
1Department of Internal Medicine, Academic Hospital-Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium.
Abstract:
Acute interstitial nephritis (AIN) is a common cause of acute renal failure. We report a case of AIN, confirmed by renal biopsy, that developed in a patient with typhoid fever due to a Salmonella hadar infection. AIN secondary to Salmonella infection is a rare complication that has only been described twice in the literature. Salmonella should be added to the list of possible causes of AIN.
Insights
Acute interstitial nephritis (AIN), a cause of kidney failure, can be triggered by Salmonella infections. This rare complication, confirmed by biopsy, suggests Salmonella should be considered in AIN cases.
Area of Science:
- Nephrology
- Infectious Diseases
- Pathology
Background:
- Acute interstitial nephritis (AIN) is a significant cause of acute kidney injury.
- Salmonella infections are typically associated with gastrointestinal illness.
- AIN as a complication of Salmonella is exceptionally rare in medical literature.
Purpose of the Study:
- To report a case of AIN secondary to Salmonella hadar infection.
- To highlight the potential for Salmonella to cause AIN.
- To contribute to the understanding of rare AIN etiologies.
Main Methods:
- Case report of a patient with typhoid fever.
- Confirmation of AIN through renal biopsy.
- Identification of Salmonella hadar as the causative agent.
Main Results:
- The patient presented with AIN.
- Renal biopsy confirmed interstitial nephritis.
- The AIN was attributed to Salmonella hadar infection.
Conclusions:
- Salmonella infection can cause acute interstitial nephritis.
- This case represents a rare instance of AIN secondary to Salmonella.
- Salmonella should be included in the differential diagnosis for AIN.
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