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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Clinical experience of simultaneous aortic operation and coronary artery bypass grafting]
Li-zhong Sun1, Ning-ning Liu, Qian Chang
1Aortic Surgery Center, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Insights
Simultaneous aortic operations and coronary artery bypass grafting (CABG) for aortic dissection carry a high mortality risk, especially with coronary involvement. However, combined aortic aneurysm repair and CABG is a safe procedure.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Context:
- Aortic dissection and aneurysms often coexist with coronary artery disease.
- Simultaneous surgical intervention presents unique challenges and risks.
- Optimal management strategies require careful patient selection and procedural planning.
Purpose:
- To evaluate the outcomes of combined aortic operations and coronary artery bypass grafting (CABG).
- To assess the safety and efficacy of these combined procedures in a cohort of patients.
- To identify risk factors associated with adverse outcomes in combined aortic and coronary surgeries.
Summary:
- Thirty-six patients underwent combined aortic operations and CABG between 1997 and 2004.
- High mortality was observed in Type A aortic dissection with coronary involvement or atherosclerosis.
- Combined aortic aneurysm repair and CABG demonstrated a safe procedural profile.
Impact:
- Highlights the increased mortality associated with Type A aortic dissection and coronary compromise.
- Recommends preoperative coronary angiography for patients over 50 with aortic aneurysms.
- Establishes the safety of combined aortic aneurysm repair and CABG procedures.
Objective:
To summarized the experience of simultaneous aortic operation and coronary artery bypass.
Methods:
Between November 1997 and September 2004, thirty-six patients who underwent combined aortic operation and coronary artery bypass graft (CABG) were reviewed with a mean age of (57 +/- 12) years (range 31 to 75). Nineteen patients were suffered from aortic dissection. There were 17 patients of aortic aneurysm, 5 aortic root aneurysm, 5 ascending aortic aneurysm, 4 aortic arch aneurysm, 3 abdominal aneurysm. Preoperational coronary angiography was performed in 1 of 10 acute type A dissection patients. The coronary arteries were involved by dissection in 7 acute type A dissection patients. The artherosclerosis of coronary artery was found during operation in 2 patients. Among 7 patients with chronic type A aortic dissection, coronary angiography was performed in 2, coronary artery was involved by dissection in 2 and coronary arterosclaerosis was founded in 3. There were 2 patients with acute or chronic type B aortic dissection. The stenosis of coronary artery was confirmed by preoperative angiography in the patients with aortic aneurysm. There were 57 coronary bypass grafts, 6 of them were artery grafts, and others were venous grafts.
Results:
The mean cardiopulmonary bypass time was (157 +/- 54) min, and the mean aortic cross clamp time was (98 +/- 31) min. Five patients with type A aortic dissection died postoperatively, 3 from heart failure leading to multi organ system failure, 1 from cerebral hernia and one from ischemia of intestinal tract. Postoperative complication included reoperation for hemorrhage in 1 patient, respiratory failure in 1 patient.
Conclusions:
Type A aortic dissection with coronary involvement or arterosclaerosis is associated with high mortality rate. Coronary artery angiography should be performed in the elder than 50 years patient with aortic aneurysm. Combined aortic aneurysm operation and CABG is a safe procedure.
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