Related Experiment Video
Updated: Aug 9, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Outbreak of epidemic methicillin-resistant Staphylococcus aureus in a regional burns unit: management and
Abid Rashid1, Livingstone K Solomon, Harry G Lewis
1Northern Ireland Plastic and Maxillofacial Service, Ulster Hospital, Dundonald, Belfast, Northern Ireland BT16 1RH, UK. Abidrashid@aol.com
Abstract:
Colonization of burn patients with methicillin-resistant Staphylococcus aureus (MRSA) is not uncommon, however an outbreak that necessitates closure of a burns unit is relatively rare. The objective of this study was to present the experience of a regional adult burns unit where an outbreak of epidemic MRSA-15 (EMRSA-15) took place. During the studied period, 176 patients were admitted to the unit, 52 with burns, 48 for elective plastic surgery procedures while the remainder belonged to other specialties. Patients admitted under burns and plastic surgery were investigated together with 46 staff members to control the outbreak. MRSA was isolated in 18 patients out of which 12 had EMRSA-15. Among the staff members, MRSA was isolated in nine of which five had EMRSA-15. The burns unit was closed to all admissions to terminate this outbreak. The MRSA positive staff members were sent on "special leave" and underwent treatment with nasal mupirocin and triclosan body wash. All staff members were able to return to work after one week's treatment. The burns unit underwent re-furbishment and decontamination while it was closed. In conclusion, the study shows that an outbreak of EMRSA was controlled successfully, however, it highlights the implications of such an event for a regional burn service with regard to staff, patients and guidelines for management.
Insights
An epidemic of methicillin-resistant Staphylococcus aureus (MRSA) in a regional burns unit was successfully controlled. This outbreak highlights the significant impact on patient care, staff, and management protocols for burn services.
Area of Science:
- Infectious Diseases
- Hospital Epidemiology
- Burn Care Management
Background:
- Colonization with methicillin-resistant Staphylococcus aureus (MRSA) is common in burn patients, but outbreaks requiring unit closure are rare.
- An epidemic strain, EMRSA-15, caused a significant MRSA outbreak in a regional adult burns unit.
Purpose of the Study:
- To document the experience and management of an EMRSA-15 outbreak in a regional adult burns unit.
- To analyze the implications of the outbreak on patient care, staff, and service provision.
Main Methods:
- Investigated 176 admitted patients (52 burns, 48 plastic surgery) and 46 staff members for MRSA.
- Implemented unit closure, staff treatment (nasal mupirocin, triclosan body wash), and unit decontamination.
- Monitored MRSA isolation rates in patients and staff.
Main Results:
- MRSA was isolated in 18 patients (12 EMRSA-15) and nine staff members (5 EMRSA-15).
- The burns unit was closed to new admissions to contain the outbreak.
- Staff treatment and unit decontamination led to successful outbreak termination, with staff returning to work after one week.
Conclusions:
- The EMRSA-15 outbreak was successfully controlled through a multi-faceted approach including unit closure and targeted treatment.
- The study underscores the critical impact of such outbreaks on regional burn services, affecting patient management, staff resources, and the need for robust infection control guidelines.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Staphylococcal Skin Infections
Mechanism of Antibiotic Resistance in MRSA
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Acute Pyelonephritis II: Diagnostic Studies and Management
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...