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Updated: Aug 9, 2026

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In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
Published on: May 12, 2023
Spectroscopic studies of the interaction between quercetin and G-quadruplex DNA
Hongxia Sun1, Yalin Tang, Junfeng Xiang
1Beijing University of Chemical Technology, Beijing 100029, China.
Bioorganic & Medicinal Chemistry Letters
|April 20, 2006
Abstract:
Quercetin is a kind of flavonoid which has been proved to exhibit anti-tumor activity. The interaction modes of quercetins with monomeric and dimeric G-quadruplexes were studied by absorption, fluorescence, CD, and (1)H NMR spectroscopies. The ligands were found to be stacked with terminal tetrads of monomeric G-quadruplexes by intercalation and bound to dimeric G-quadruplexes by groove binding.

