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Updated: Feb 6, 2026

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Intratracheal Administration of Dry Powder Formulation in Mice
Published on: July 25, 2020
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Administration of antibody to the lung protects mice against pneumonic plague
Jim Hill1, Jim E Eyles, Stephen J Elvin
1Defence Science and Technology Laboratory, Porton Down, Wiltshire SP4 OJQ, United Kingdom. jhill@dstl.gov.uk
Infection and Immunity
|April 20, 2006
Abstract:
Intratracheal delivery of aerosolized monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a model of pneumonic plague. These data support the utility of inhaled antibodies as a fast-acting postexposure treatment for plague.
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