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Published on: September 9, 2020
Oncologic outcome of parosteal osteosarcoma
Manabu Hoshi1, Seiichi Matsumoto, Jun Manabe
1Department of Orthopaedic Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-10-6 Ariake, Tokyo 135-8550, Japan.
International Journal of Clinical Oncology
|April 20, 2006
Summary
Parosteal osteosarcoma (POS) in the distal femur can be surgically treated with wide resection, often without biopsy, leading to excellent outcomes. This approach preserves limb function and achieves disease-free survival in all patients.
Area of Science:
- Orthopedic Oncology
- Skeletal Radiology
- Surgical Pathology
Background:
- Parosteal osteosarcoma (POS) is a rare bone tumor.
- Evaluating clinical features and surgical outcomes of POS is crucial for treatment planning.
Purpose of the Study:
- To assess the clinical characteristics and surgical results of parosteal osteosarcoma.
- To determine the feasibility of wide resection without biopsy for POS.
Main Methods:
- Retrospective review of nine patients with parosteal osteosarcoma.
- Analysis of clinical information, surgical procedures, and oncologic outcomes.
- Follow-up assessment of disease recurrence and limb function.
Main Results:
- All nine tumors were located in the distal femur, arising from the metaphyseal area.
- Wide resection was performed in all cases, with margins of 1-2 cm.
- Biopsies were performed in only two cases; characteristic radiographic findings allowed for direct resection in 77.8% of cases.
- Autobone grafting or total knee replacement (TKR) was used for reconstruction based on tumor characteristics.
- No adjuvant treatments were administered.
Conclusions:
- Parosteal osteosarcoma exhibits distinct radiographic features, potentially enabling wide resection without prior biopsy.
- This approach may improve limb function by minimizing tissue contamination and resection extent.
- All patients achieved disease-free survival with good clinical courses over a mean follow-up of 115.1 months, suggesting the safety and efficacy of this surgical strategy.
