Related Experiment Video
Updated: Aug 9, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
[Arterial stiffness--pathophysiological significance and practical aspects of assessment]
Paweł Stróźecki1, Michał Kozłowski, Robert Kurowski
1Katedra i Klinika Nefrologii, Nadciśnienia Tetniczego i Chorób Wewnetrznych Collegium Medicum im L Rydygiera w Bydgoszczy. nerka@nerka.mtl.pl
Insights
Arterial stiffness, a key indicator of vascular health, increases with age and is linked to cardiovascular issues. Assessing arterial stiffness may offer a new cardiovascular risk parameter and therapeutic target.
Area of Science:
- Cardiovascular Physiology
- Vascular Biology
Context:
- Arterial stiffness is a crucial determinant of cardiovascular health, influenced by arterial structure and function.
- It progresses with age, leading to increased systolic and pulse pressure, and decreased diastolic blood pressure.
- Elevated arterial stiffness is observed in conditions like hypertension, chronic renal failure, and diabetes, and is an independent predictor of mortality.
Purpose:
- To explore the multifaceted nature of arterial stiffness.
- To review methods for assessing arterial stiffness.
- To highlight the prognostic significance and potential therapeutic implications of arterial stiffness.
Summary:
- Arterial stiffness is a dynamic vascular property that worsens with age and is associated with hypertension, diabetes, and kidney disease.
- It contributes to cardiovascular complications like left ventricular hypertrophy.
- Various methods and indices exist to assess systemic, regional, and local arterial stiffness.
Impact:
- Arterial stiffness assessment can serve as a valuable cardiovascular risk parameter.
- It may become a future therapeutic target, with potential benefits from treatments like angiotensin converting enzyme inhibitors.
- Understanding and managing arterial stiffness is crucial for improving cardiovascular outcomes.
Abstract:
Arterial stiffness is a dynamic property which depends on structure and function of arteries. Arterial stiffness progresses with age and it is an important factor leading to increase of systolic and pulse pressure and decrease in diastolic blood pressure. Increased arterial stiffness was also found in hypertension, chronic renal failure and diabetes. Arterial stiffness is an independent prognostic factor of mortality in hypertension and end-stage renal disease. Arterial stiffening leads to cardiovascular complications such as left ventricular hypertrophy. Many methods to assess different aspects of arterial stiffness: systemic, regional and local were developed. Various indicies of arterial stiffness were defined and are used in clinical investigations. Arterial stiffness is a dynamic parameter. Decrease in blood pressure leads to decrease of arterial stiffness. Many authors suggest, that angiotensin converting enzyme inhibitors may exert favourable effect, irrespective of blood pressure. Arterial stiffness assessment may become a cardiovascular risk parameter and a therapeutic goal.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Peripheral Artery Disease I: Introduction
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease IV: Nursing Management
