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[Focal nodular hyperplasia].

Radoje Colović, Nikica Grubor, Vladimir Radak

Srpski Arhiv Za Celokupno Lekarstvo

|April 21, 2006

Summary

Focal nodular hyperplasia (FNH), a common liver tumor, is often found in women using oral contraceptives. This case highlights FNH discovered incidentally in a young woman without hormone use, emphasizing diverse presentations of this liver lesion.

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Area of Science:

Hepatobiliary Medicine
Diagnostic Imaging
Surgical Pathology

Background:

Advancements in imaging technologies like ultrasonography, CT, and MRI have increased the detection of both symptomatic and asymptomatic liver tumors.
Focal nodular hyperplasia (FNH) is a benign liver tumor, frequently asymptomatic, predominantly affecting women of reproductive age, often linked to oral contraceptive use.

Observation:

A 27-year-old woman, with no history of oral contraceptive or hormone use, presented with an incidentally discovered left lobe liver tumor during a routine investigation for psychiatric issues.
The resected tumor consisted of two nodes, measuring 70x58x47 mm and 20x20x20 mm, with the larger node exhibiting a characteristic pale, central stellate scar.

Findings:

Histopathological examination confirmed the diagnosis of focal nodular hyperplasia (FNH).

Implications:

This case underscores that FNH can occur in women without typical risk factors such as oral contraceptive use, necessitating consideration in differential diagnoses for liver lesions.
The successful surgical resection (left lateral bisegmentectomy) resulted in an uneventful recovery and long-term symptom-free survival for the patient, demonstrating effective management of FNH.

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