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Updated: Aug 9, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Aspirin in the treatment of acute migraine attacks
Hans-Christoph Diener1, Christian Lampl, Peter Reimnitz
1Department of Neurology, University Duisburg-Essen, Hufelandstrasse 55, 45122, Essen, Germany. h.diener@uni-essen.de
Abstract:
Acetylsalicylic acid (aspirin or ASA) has been used for many years as an analgesic, antipyretic and anti-inflammatory drug. In recent years, evidence for its effectiveness in migraine headache has been demonstrated in several clinical trials. The effervescent highly buffered preparation of aspirin was shown to be effective, safe and well tolerated compared with placebo or other treatment options. The effervescent aspirin preparation is at least as effective as the combination of aspirin plus metoclopramide, but has fewer side effects. This review summarizes and analyzes clinical data of aspirin in the treatment of acute migraine attacks with respect to the different galenic formulations.
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