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A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
Published on: February 3, 2016
Stenosis in hemodialysis arteriovenous fistula: evaluation and treatment
Rodrigo P Campos1, Marcelo M Do Nascimento, Domingos C Chula
1Evangelic Faculty of Parana, Evangelic University Hospital of Curitiba, Curitiba, Brazil.
Insights
Arteriovenous fistula stenosis can impair hemodialysis adequacy. Early detection through surveillance, including physical exams and intra-access pressure, is crucial for timely intervention and improved patient outcomes.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Vascular access complications significantly increase morbidity and mortality in stage 5 chronic kidney disease patients.
- Arteriovenous fistula is the preferred vascular access for hemodialysis due to its high patency and low complication rates.
- Stenosis is the primary cause of arteriovenous fistula dysfunction, necessitating vigilant surveillance.
Purpose of the Study:
- To highlight the importance of arteriovenous fistula surveillance for detecting stenosis.
- To discuss various surveillance methods, including physical examination, intra-access pressure, recirculation, and blood flow measurements.
- To emphasize the significance of timely correction procedures for arteriovenous fistula stenosis.
Main Methods:
- Case report of a hemodialysis patient with inadequate Kt/V.
- Investigation involving physical examination and intra-access pressure monitoring.
- Diagnosis of venous stenosis via Doppler ultrasound.
Main Results:
- Abnormal physical examination findings and altered intra-access pressure measurements indicated fistula dysfunction.
- Doppler ultrasound confirmed venous stenosis as the cause.
- Percutaneous transluminal angioplasty was successfully performed to treat the stenosis.
Conclusions:
- Early detection of arteriovenous fistula stenosis through comprehensive surveillance is vital for maintaining hemodialysis adequacy.
- Intra-access pressure monitoring and Doppler ultrasound are effective diagnostic tools.
- Prompt angioplasty can correct stenosis and improve patient outcomes.
Abstract:
Vascular access complications are one of the main causes associated with an increase in morbidity and mortality in stage 5 chronic kidney disease patients. The arteriovenous fistula is regarded as the vascular access of choice for hemodialysis (HD) because of its superior patency and lower complication rates. Stenosis is considered the major cause of dysfunction of arteriovenous fistula. Despite the relatively low thrombosis rates of arteriovenous fistula, surveillance programs are necessary for detection of stenosis. We report a case of a HD patient who had never achieved an adequate Kt/V since the start of maintenance HD. During the investigation, abnormal findings were found on physical examination of the fistula, in addition to an alteration in intra-access pressure (IAP) measurements. A venous stenosis was diagnosed by Doppler ultrasound and then promptly treated with percutaneous transluminal angioplasty. The purpose of the discussion is to highlight the peculiarities of arteriovenous fistulae, methods of surveillance, including physical examination, IAP, recirculation, and measurements of blood flow, and the importance of the correction procedures for the stenosis.
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