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Updated: Aug 9, 2026

A High-throughput Assay to Assess and Quantify Neutrophil Extracellular Trap Formation
Published on: January 29, 2019
Anti-neutrophil cytoplasm-associated glomerulonephritis
Matthew David Morgan1, Lorraine Harper, Julie Williams
1Division of Immunity and Infection, The Medical School, University of Birmingham, Vincent Drive, Birmingham, United Kingdom.
Abstract:
Wegener's granulomatosis, microscopic polyangiitis, and renal limited vasculitis are associated with circulating anti-neutrophil cytoplasm antibodies and are an important cause of rapidly progressive glomerulonephritis. This review gives an account of recent advances in the understanding of the pathogenesis underlying these conditions and how these may lead to future treatments. Consideration is given to recent clinical trials in the management of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitides.
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