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["Descending necrotizing mediastinitis" due to deep neck infections. Incidence and management]
A Sandner1, J Börgermann, S Kösling
1Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Martin-Luther-Universität, Halle-Wittenberg. annett.sandner@medizin.uni-halle.de
Background:
"Descending necrotizing mediastinitis" (DNM) is a rare but potentially life-threatening complication of deep neck infections caused by the rapid downward spread of a oropharyngeal infection along the facial planes into the mediastinum.
Material And Methods:
Between June 1997 and December 2004, 6 patients with DNM were treated in our department. The primary etiology was a peritonsillar abscess in 2 cases, a parapharyngeal abscess in 3 cases and in 1 case an odontogenic abscess. Most patients presented with risk factors such as diabetes mellitus or alcoholism, the mean age was 44.3 years and the mean duration of signs before diagnosis was 6.3 days. Thoracotomy was associated with the cervical approach in 4 cases and tracheostomy was also performed in 4 cases.
Results:
Four patients were successfully treated, the mean duration of hospitalisation was 48.2 days and 2 patients died from sepsis and multiorgan failure despite intensive treatment.
Conclusions:
Descending necrotizing mediastinitis must be detected as soon as possible. The mean symptoms are persistent complaints after treatment of oropharyngeal infections, which may be masked by analgetic treatment. Only an immediate computer tomographic scanning, aggressive surgical drainage and debridement of the neck and the mediastinum can reduce the high mortality rate.
Insights
Descending necrotizing mediastinitis (DNM) is a severe infection spreading from the neck to the chest. Early diagnosis and aggressive surgical intervention are crucial for survival.
Area of Science:
- Medical research
- Surgical pathology
- Infectious diseases
Background:
- Descending necrotizing mediastinitis (DNM) is a rare, life-threatening complication of deep neck infections.
- It results from the rapid downward spread of oropharyngeal infections into the mediastinum via facial planes.
Observation:
- A study treated 6 patients with DNM between 1997 and 2004.
- Common causes included peritonsillar, parapharyngeal, and odontogenic abscesses.
- Risk factors like diabetes and alcoholism were noted, with a mean diagnosis delay of 6.3 days.
Findings:
- Four out of six patients survived, with a mean hospitalization of 48.2 days.
- Two patients died from sepsis and multiorgan failure despite intensive care.
Implications:
- Prompt detection of DNM is critical.
- Persistent symptoms post-oropharyngeal infection treatment warrant investigation, potentially masked by analgesics.
- Immediate CT scans, aggressive surgical drainage, and debridement are essential to reduce high mortality rates.
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