Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Lowering cholesterol in the elderly--yes, no, or maybe?].

M Gogol1

  • 1Chefarzt der Klinik für Geriatrie, Krankenhaus Lindenbrunn. gogol@krankenhaus-lindenbrunn.de

MMW Fortschritte Der Medizin
|April 22, 2006
PubMed
Summary

Statins are recommended for cardiovascular disease prevention in older adults, but evidence is limited for those over 80. Multidrug statin therapy is not advised due to potential risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extracellular proteinases of Candida species pathogenic yeasts.

Molecular oral microbiology·2017
Same author

[Mobility of elderly people : Progress in assessment and intervention].

Zeitschrift fur Gerontologie und Geriatrie·2016
Same author

[The Choosing Wisely Initiative of the German Society of Internal Medicine : Recommendations of the German Society for Endocrinology and the German Society for Geriatrics].

Der Internist·2016
Same author

Influence of central nervous system-acting drugs on results of cognitive testing in geriatric inpatients.

Zeitschrift fur Gerontologie und Geriatrie·2014
Same author

[Geriatric trauma centers - requirements catalog. An initiative to promote and guarantee the quality of care of elderly trauma patients receiving inpatient care].

Zeitschrift fur Gerontologie und Geriatrie·2014
Same author

[Geriatric trauma care in Germany. On the way to providing better care].

Zeitschrift fur Gerontologie und Geriatrie·2014

Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Pharmacology

Context:

  • Limited data exists on statin use for cholesterol management in geriatric patients.
  • Current guidelines from IOWiG and NICE support statin use in various cardiovascular conditions.
  • Evidence for statin efficacy in patients over 75 is primarily for coronary artery disease (CAD) with elevated LDL cholesterol, up to age 80.

Purpose:

  • To review the current evidence and guidelines for statin application in geriatric patients.
  • To assess the benefits and risks of statin therapy in older adults with cardiovascular disease.
  • To evaluate the appropriateness of statin use in primary and secondary cardiovascular prevention for the elderly.

Summary:

  • Statins are recommended by IOWiG and NICE for cardiovascular disease prevention in adults.
  • Specific evidence supporting statin superiority in patients over 75 is limited to CAD with high LDL cholesterol up to age 80.
  • Multidrug therapy involving statins in geriatric patients is cautioned against due to risks of side effects and drug interactions.

Impact:

  • Highlights the need for more research on statin efficacy and safety in the elderly population.
  • Informs clinical decision-making regarding statin prescription for geriatric patients.
  • Emphasizes the importance of individualized treatment plans considering potential drug interactions and side effects in older adults.

Related Experiment Videos