Related Experiment Video
Updated: Aug 9, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Optical coherence tomographic pattern of fluorescein angiographic leakage site in acute central serous
Nazimul Hussain1, Arumugam Baskar, Ls Mohan Ram
1Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Andhra Pradesh, India. nazimul@lvpei.org
Purpose:
To study the optical coherence tomography (OCT) pattern of the fluorescein angiographic leakage in acute central serous chorioretinopathy (CSCR).
Methods:
This is a non-interventional pilot case study. OCT line scan was performed over the fluorescein angiographic leak site in eyes clinically diagnosed acute CSCR. Clinical fundus photograph, site of leakage on fundus fluorescein angiography and corresponding OCT were analysed.
Results:
The mean age of 10 consecutive patients was 38.8 +/- 6.9 years. Six patients were male and the mean duration of symptom was 7 days. Six eyes (60%) showed a characteristic dipping pattern of neurosensory retina with intervening hyper-reflective echoes suggestive of fibrin over the leakage site. All these eyes had ink-blot leak and subretinal fibrin.
Conclusions:
Ink-blot leak in acute CSCR with subretinal fibrin generates a dipping morphological pattern on OCT.