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Updated: Aug 1, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
Three-dimensional X-ray coronary angiography in the porcine model: A feasibility study
Volker Rasche1, Babak Movassaghi, Michael Grass
1Department Technical Systems, Philips Research Laboratories, Röntgenstr. 24-26, D-22315 Hamburg, Germany. Volker.Rasche@uniklinik-ulm.de
Rationale And Objectives:
Three-dimensional high-spatial-resolution angiograms of the coronary arteries were acquired with an electrocardiogram-gated three-dimensional rotational angiography technique on an interventional X-ray system.
Materials And Methods:
During selective injection of contrast material in the left and right coronary artery, projection images were obtained in eight pigs during a continuous rotation of the X-ray gantry over an angular range of 180 degrees within 8 seconds.
Results:
Three-dimensional tomographic reconstruction depicted the proximal, medial, and distal sections of the main arteries as well as the main bifurcations in multiple cardiac phases in all animals.
Conclusions:
For the first time, this feasibility study shows that a three-dimensional angiogram of the coronary arteries can be obtained intraprocedurally in a conventional interventional suite by means of tomographic reconstruction from projection images.

