Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transient ST-segment-elevation during pulmonary vein ablation using circumferential coiled microelectrodes in a

Tim Risius1, Thorsten Lewalter, Berndt Lüderitz

  • 1Department of Cardiology, University Hospital Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. risius@uke.uni-hamburg.de

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
|April 22, 2006
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study.

Nature medicine·2024
Same author

Impact of atrial fibrillation on 1-year outcome in patients with implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator: results from the German DEVICE Registry.

Journal of thoracic disease·2024
Same author

Cardiac, possible cardiac, and likely non-cardiac origin of chest pain : A hitherto underestimated parameter in German chest pain units.

Herz·2023
Same author

Hybrid machine learning to localize atrial flutter substrates using the surface 12-lead electrocardiogram.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2022
Same author

CVAR-Seg: An Automated Signal Segmentation Pipeline for Conduction Velocity and Amplitude Restitution.

Frontiers in physiology·2021
Same author

Cycle length statistics during human atrial fibrillation reveal refractory properties of the underlying substrate: a combined in silico and clinical test of concept study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2021

ST-segment elevation during pulmonary vein mapping for paroxysmal atrial fibrillation is a reversible phenomenon. This study found no lasting damage, suggesting vasospasm as a potential cause.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Paroxysmal atrial fibrillation (PAF) is often triggered by focal ectopies in the pulmonary veins (PVs).
  • The BITMAP Study evaluated a novel catheter for mapping and isolating PVs in PAF patients.

Purpose of the Study:

  • To prospectively investigate the safety and efficacy of a new catheter design for PAF ablation.
  • To report the occurrence and characteristics of ST-segment elevation during left atrial and PV mapping.

Main Methods:

  • Radiofrequency catheter ablation using a microcatheter with circumferential mapping electrodes in 43 PAF patients.
  • Monitoring for ST-segment changes and symptoms during catheter placement in the left atrium and superior PVs.

Main Results:

Related Experiment Videos

  • ST-segment elevation (>0.2 mV) with thoracic discomfort occurred in 4/43 patients.
  • These transient changes resolved spontaneously within minutes without complications like pericardial effusion or coronary issues.
  • Echocardiography and coronary angiography ruled out other causes.

Conclusions:

  • ST-segment elevation during left atrial and PV mapping in PAF patients appears to be a common, reversible phenomenon.
  • The study demonstrated no cardiovascular or cerebral damage during the procedure or follow-up.
  • Autonomic dysregulation leading to vasospasm is a potential, though unconfirmed, mechanism.