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Evaluation of cerebral hemodynamics with computed tomography perfusion using gadolinium as an alternative to

Roham Moftakhar1, David B Niemann, Aquilla Turk

  • 1Department of Neurosurgery, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA.

Journal of Computer Assisted Tomography
|April 22, 2006
PubMed

Insights

Computed tomography (CT) perfusion using gadolinium contrast is a safe alternative for patients with chronic renal failure. This case study demonstrates successful CT perfusion in a patient with severe renal impairment, avoiding further complications.

Area of Science:

  • Radiology
  • Nephrology
  • Neurology

Background:

  • Computed tomography (CT) perfusion imaging is crucial for assessing brain perfusion.
  • Iodinated contrast agents commonly used in CT perfusion pose risks for patients with impaired renal function or contrast allergies.
  • Chronic renal failure presents a significant challenge for contrast-enhanced imaging procedures.

Observation:

  • A 63-year-old male patient with a history of chronic renal failure experienced worsening renal function after a left cervical internal carotid artery stent placement due to 70% stenosis.
  • The patient presented with a left hemisphere perfusion deficit, necessitating advanced imaging.
  • Standard iodinated contrast agents were contraindicated due to the patient's renal status.

Findings:

  • CT perfusion was successfully performed using gadolinium-based contrast agent.
  • The use of gadolinium contrast did not lead to further renal complications in this patient with pre-existing chronic renal failure.
  • The imaging successfully evaluated the left hemisphere perfusion deficit.

Implications:

  • Gadolinium contrast represents a viable and safer alternative for CT perfusion in patients with chronic renal failure.
  • This approach can help avoid contrast-related nephropathy in vulnerable patient populations.
  • Successful application of gadolinium in CT perfusion may expand imaging options for patients with contraindications to iodinated contrast agents.

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