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Dilated cardiomyopathy and adipic aciduria in nutritional rickets

Rahul Roy1, Wael El-Matary, Gordon Gladman

  • 1Department of Cardiology, Metabolism and Biochemistry, Royal Liverpool Children's NHS Trust, Liverpool, UK.

Pediatric Emergency Care
|April 22, 2006
PubMed

Insights

Nutritional rickets causing hypocalcemia is a rare cause of dilated cardiomyopathy and not a recognized cause of adipic aciduria. This report details the first case of adipic aciduria linked to hypocalcemia and dilated cardiomyopathy.

Area of Science:

  • Pediatric Cardiology
  • Nutritional Disorders
  • Metabolic Disorders

Background:

  • Nutritional rickets can lead to hypocalcemia.
  • Hypocalcemia is a rare cause of dilated cardiomyopathy.
  • Dicarboxylic aciduria is not typically associated with rickets.

Observation:

  • A case of a patient presented with dilated cardiomyopathy.
  • The patient also exhibited adipic aciduria.
  • Hypocalcemia was identified as the underlying cause.

Findings:

  • This is the first reported case of adipic aciduria.
  • The adipic aciduria was secondary to hypocalcemia.
  • The hypocalcemia was caused by nutritional rickets.

Implications:

  • Highlights a rare presentation of nutritional rickets.
  • Expands understanding of metabolic derangements in rickets.
  • Suggests a need to consider adipic aciduria in pediatric cardiomyopathy cases with hypocalcemia.

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